The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the Lions.

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ACL is good, thank you GOD. I'll be back ...

Unfortunately, the season finale came with one final trick up its sleeve as running back Isaac Guerendo was carted off the field early in the first quarter. On the broadcast, sideline reporter ...

One key player who was questionable to suit up this week is Isaac Guerendo, the 49ers running back, but good news was released on Saturday that he is expected to play tonight. He has averaged an ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was carted off to the locker room for evaluation ...

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports. Guerendo picked up foot and hamstring injuries in Week 15 ...

Guerendo (foot/hamstring) doesn't have a designation for Monday's game versus the Lions, Cam Inman of The San Jose Mercury News reports. Guerendo managed limited practices Thursday and Friday due ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped five of their last six matchups. The 49ers last met Detroit in the NFC ...

Jahmyr Gibbs and Isaac Guerendo will be the featured fantasy football running backs on Monday Night Football in Week 17. While the Detroit Lions-San Francisco 49ers game has no implications on the ...

SANTA CLARA, Calif. -- After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to play Monday night against the Detroit Lions. Guerendo ...