Lyonne lurked at the margins of Hollywood a long time, an eccentric with self-confessed niche appeal. But in recent years, she’s moved closer to the center—or maybe the center has finally come to her.

Ahead of hosting the AMPAS Sci-Tech Awards on Friday, Lyonne also called AI a "fair and formidable foe" to the movie industry Natasha Lyonne ... to her throughout her life. "I love movies ...