An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

New research adds to our understanding of the function of the human genome. An international team of researchers has made ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

An international group of scientists has made a significant advancement in their understanding of the regulation of gene expression throughout the human genome.

The greatly diverged chicken and zebrafish insulin promoters lack mammalian A boxes ... regulatory element may be influential in insulin expression, perhaps playing a role in energy homeostasis.

The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...