SCDOT says the closures will begin on Sunday, Jan. 26 at 7 p.m.
The eastbound exit ramp at Big Cabin on I-44 and Will Rogers Turnpike is temporarily shut down due to an overturned semi.
Hitting the road soon? Check our live traffic updates to see if your route is clear.
Work crews will be working Friday through Monday morning on the following closures and restrictions on multiple freeways for construction this weekend.