Pelareorep treatment drives coordinated immune activation and tertiary lymphoid structure formation Translational data suggest potential to boost ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

The immune system has two separate responses, which are orchestrated to optimize protection against pathogens. The first ...

Type 1 diabetes (T1D) is an autoimmune disease characterized by the immune-mediated destruction of pancreatic B cells. While autoreactive T cells are key ...

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated ...

The Bacille Calmette–Guérin (BCG) vaccine, originally developed for tuberculosis prevention, has garnered considerable attention for its capacity to reprogramme the innate immune system. Beyond its ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

Microbial threats against human health are only growing. Luckily, researchers are developing new vaccines that are up to the challenge.

It starts with a sneeze. Someone on the subway didn't cover their mouth and now a cloud of invisible invaders hangs in the air. Before you even step off the train, your immune system has already begun ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...