CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...
Please provide your email address to receive an email when new articles are posted on . The researchers’ three-biomarker algorithm successfully identified esophageal cancer, BE and high-grade ...
The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...
CDCA7 binds to the hemimethylation site in the major groove of nucleosomal DNA without base-flipping. R274 confers preferential binding of CDCA7 to a hemimethylated CpG. The side chain of Q275 is ...
DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early biological changes that may explain how diet leaves a ...
The scientists at deCODE Genetics, a subsidiary of Amgen, sought to deepen the understanding of cis-acting influences of sequence variants on CpG methylation. In the study, the scientists were able to ...
The global DNA methylation market size was valued at US$ 1.9 Bn in 2025 and is projected to reach US$ 7.7 Bn by 2036, growing ...
This article is based on a poster originally authored by Archana Bettadapur, Adam Barner, Melissa Netwal, Sanika Khare, Cam Jansen, and Dominic Skinner. Many epigenetics applications leverage the ...