Upon starting methotrexate treatment, LDH and albumin levels may be signals for AKIs in patients with hematologic malignancies. Among patients with hematologic malignancies treated with methotrexate, ...

Methotrexate is a strong medicine. The FDA approved it to treat adults with severe, disabling psoriasis that cannot be controlled with medicine applied to the skin or light treatments. Methotrexate ...

A widely used treatment for rheumatoid arthritis may offer an unexpected cardiovascular benefit. Methotrexate has been a staple treatment for rheumatoid arthritis for decades, valued for its ability ...

Disease-modifying drug therapies are being sought intensively for osteoarthritis (OA), but none have proved out thus far. A previous trial in patients with OA of the hand had found that methotrexate ...

Methotrexate significantly lowers systolic blood pressure in newly diagnosed RA patients compared to sulfasalazine, potentially reducing cardiovascular risk. The study provides prospective comparative ...

July 22, 2009 — Intensive treatment with methotrexate may be helpful in early rheumatoid arthritis despite greater adverse events vs conventional treatment, according to the results of a study ...

Twenty doses of outpatient HD-MTX with glucarpidase were administered to seven patients. After 20 of 20 (100%) treatments, serum MTX levels were reduced to <100 nmol/L. Treatments were well-tolerated, ...

Adalimumab monotherapy and combination with methotrexate showed similar drug survival and PASI75 response rates in plaque psoriasis patients. Methotrexate reduced antidrug antibody levels but did not ...

Medically reviewed by Scott Zashin, MD Key Takeaways People taking methotrexate should avoid alcohol because it can increase the risk of liver damage.Some NSAIDs like aspirin should not be taken with ...

Subcutaneous tocilizumab, either as monotherapy or in combination with methotrexate, demonstrated greater efficacy than methotrexate alone and was well tolerated in patients with active rheumatoid ...