Loop diuretics are widely used, especially in patients with hypertension or heart failure plus renal dysfunction. Such patients are particularly susceptible to untoward drug effects. It is, therefore, ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Big clinical trials of loop diuretics for keeping patients stable after discharge from a heart-failure (HF) hospitalization have been in short supply, so firm guideline recommendations on the matter ...

Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use. In a prospective, double-blind, ...

Diuretics are a class of medications commonly known as "water pills." There are several different classes of diuretics, each of which works differently in the kidneys to help rid the body of extra ...

Please provide your email address to receive an email when new articles are posted on . Acute and chronic HF are associated with sodium retention leading to volume overload and edema. Much of the ...

Diuretic therapy remains a cornerstone in the management of heart failure, targeting intravascular and interstitial volume overload to alleviate symptoms, improve exercise tolerance and reduce ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...

Please provide your email address to receive an email when new articles are posted on . There was no link found between ever use of loop diuretics and changes in bone mineral density, falls and ...

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...