A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development ...
The research team discovered that Arvcf knockout significantly reduces the neuronal abundance within the VTA and weakens ...
A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice. Published in ...
Mouse models for hemophilia A are commonly generated by factor VIII (FVIII) knockout, however, these mice rapidly develop anti-FVIII antibodies during repetitive FVIII administration. To overcome this ...
More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, ...
There are over 70 genes that have been associated with autism spectrum disorder, but some of them are only the cause of ASD in a handful of patients. While each those genes can provide some insight ...
Explore the SHANK3 knockout model to enhance research in Phelan-McDermid syndrome and neurodevelopmental disorders.
The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts.
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