Jamie-Lynn Sigler is opening up about playing TV or movie characters with multiple sclerosis, more than two decades after she was diagnosed with the disease. The 44-year-old actor plays a doctor with ...

Christina Applegate and Jamie-Lynn Sigler candidly opened up about how their children are navigating their moms' experience with multiple sclerosis. Sigler shared that she was recently watching the ...

Jamie-Lynn Sigler says ‘every character I play has MS, whether we talk about it or not’ - Exclusive: Sigler, who was diagnosed with MS in 2002, spoke to ‘The Independent’ ahead of her guest-starring r ...

After a three-year break from television, The Sopranos actor Jamie-Lynn Sigler is returning to the small screen in an important new guest role on ABC’s Grey’s Anatomy. According to Deadline, Sigler ...

From 'The Sopranos' to 'Grey’s Anatomy,' the actress shares how living with MS has made her a more present parent and powerful advocate.

EXCLUSIVE: Big Sky alumna Jamie-Lynn Sigler is returning to ABC with a guest-starring role on the network’s hit medical drama Grey’s Anatomy. Appearing in the Jan. 15 Episode 2208, “Heavy on Me,” ...

The role was specifically created for Sigler, who has lived with the chronic autoimmune disease for over two decades. She first went public about her battle with MS in 2016 and has become an outspoken ...