Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

Researchers from the NeuroAD group (Neuropathology of Alzheimer's Disease) within the Department of Cell Biology, Genetics and Physiology at the University of Málaga, also affiliated with ...

A newly developed system to deliver tiny capsules containing anti-inflammatory proteins to specific parts of the brain may help fight Alzheimer’s and Parkinson’s diseases. AstroCapsules, described in ...

Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.

Researchers from the NeuroAD group (Neuropathology of Alzheimer's Disease) within the Department of Cell Biology, Genetics and Physiology at the University of Málaga, also affiliated with ...

The human brain contains about 86 billion neurons. These cells fire electrical signals that help the brain store memories and send information and commands throughout the brain and the nervous system.

Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state. Astrocytes are ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...