Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double helix—Crick laid out what he called the “central dogma” of molecular ...

There are only about 20,000 different genes in the human genome, yet our bodies are filled with an incredible diversity of cell types performing innumerable functions. The key to that diversity in ...

New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...