General practitioner examining a patient's hand for signs of rheumatoid arthritis. A breakthrough in cancer and autoimmune disease therapy could unlock a whole new frontier in medicine. Scientists are ...

Checkpoint inhibitors are a groundbreaking class of cancer treatment, but they come with two frustrating challenges. In some cases, tumors show no initial response, rendering the therapy ineffective ...

One of the best ways to defeat cancer is by rousing the immune system to attack it. Experts have thought that immune cells had to be inside of tumors for one type of immunotherapy, known as checkpoint ...

A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. The ...

Experts at Cincinnati Children's report proof-of-concept results that may sharply reduce the risk of a lethal side effect that has negatively impacted the use of revolutionary cancer immunotherapies ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

Please provide your email address to receive an email when new articles are posted on . Black and Hispanic patients continue to be underrepresented in immune checkpoint inhibitor trials. Almost ...

Subcutaneous immunotherapy injections for cancer, such as immune checkpoint inhibitors, are an emerging therapy that may replace some traditional intravenous infusions. Common side effects include ...

It often starts with something small—a dark spot on the skin that looks a little off. A dermatologist takes a closer look, runs a biopsy, and soon after, the diagnosis arrives: melanoma. If the cancer ...

When immune checkpoint inhibitors are used in cancer treatment, in some cases it can lead to severe inflammation and damage to heart tissue. Histology images of mouse heart tissue illustrate the ...

Please provide your email address to receive an email when new articles are posted on . Roughly 20% of individuals treated with immune checkpoint inhibitors respond. Response rates began to plateau in ...

A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. The ...