Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

In addition, regulatory sites on prokaryotic DNA are typically located close to transcription promoter sites — and this plays an important part in gene expression. For an example of how this ...

For the study, Reilly and his colleagues set out to understand how non-coding regions of DNA known as "enhancers" and ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

They also found that the three transcription factors co-occupy genes' promoter regions to regulate each others' activity. To characterize transcriptional regulation in human embryonic stem cells ...

Just like other transcription factors, HSF5 binds to DNA promoters to regulate gene expression. What distinguishes HSF5 is its unique target specificity. The research revealed that the DNA motif ...

New analyses find that divergent transcription, in which one promoter directs the expression of two adjacent genes oriented in opposite directions, is conserved across all domains of life. Jack is a ...

Chinese scientists have uncovered two major genes responsible for sorghum's double-grain spikelet, which dramatically enhance grain number and crop yield. A substantial 35.7-kilobase intrachromosomal ...

On track to declare two in vivo editing development candidates via gene upregulation, one in HSCs and one in liver, in mid-2025Company to present further in vivo HSC preclinical data and further in ...

Calculations of homology between the different insulin promoters and the human version ... are in agreement with the opinion that vertebrate genes and immediate upstream flanks are highly ...