The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be complete in time for the upcoming NFL season.

San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona Cardinals. On San Francisco's opening series and on Guerendo's second carry,

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions.

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped five of their last six matchups. The 49ers last met Detroit in the NFC Championship as the heavy favorites, but this contest isn't a deciding factor for which team will reach the Super Bowl.

San Francisco 49ers rookie running back Isaac Guerendo shared positive news on Monday morning, revealing via social media that he avoided a dreaded ACL injury, which would have jeopardized his 2025 season.